Gene mutation tied to higher obesity risk in kids - WICU12 HD WSEE Erie, PA News, Sports, Weather and Events

Gene mutation tied to higher obesity risk in kids

Updated:

THURSDAY, Oct. 24 (HealthDay News) -- Obesity is on the rise among children, and a particular genetic mutation might play a role for some kids, a new study suggests.

Researchers in Britain conducted genetic analyses of more than 2,100 severely obese youngsters. They found that those with mutations in the KSR2 gene had larger appetites and slower metabolism than those with a normal copy of the gene, according to the study published in the Oct. 24 issue of the journal Cell.

"Changes in diet and levels of physical activity underlie the recent increase in obesity; however, some people gain weight more easily than others," study author Sadaf Farooqi, of the University of Cambridge, noted in a journal news release. "This variation between people is largely influenced by genetic factors. The discovery of a new obesity gene, KSR2, demonstrates that genes can contribute to obesity by reducing metabolic rate -- how well the body burns calories."

The findings could someday lead to new treatments for obesity and type 2 diabetes, the researchers said.

Farooqi and colleagues had previously found that deleting the KSR2 gene led to obesity in mice, highlighting the gene's role in controlling energy balance and metabolism. These findings confirm KSR2's role in the regulation of weight and metabolism in humans.

"This work adds to a growing body of evidence that genes play a major role in influencing a person's weight and may be useful for developing new ways to treat people who are heavy and develop diabetes," Farooqi said.

More information

The American Academy of Pediatrics has more about childhood obesity.

Copyright © 2013 HealthDay. All rights reserved.

*DISCLAIMER*: The information contained in or provided through this site section is intended for general consumer understanding and education only and is not intended to be and is not a substitute for professional advice. Use of this site section and any information contained on or provided through this site section is at your own risk and any information contained on or provided through this site section is provided on an "as is" basis without any representations or warranties.
Powered by WorldNow
3514 State St. Erie, PA 16508
Newsroom: (814)454-8812
Toll Free: 1(800)454-8812
Business offices: (814)454-5201
WICU FCC Filing
WSEE FCC Filing
Share:
Share Stories
Submit your stories to our site!
Share Photos
Share your photos in our community galleries
Mobile:
Mobile Site
Be sure to stay constantly updated with the power of WICU12 and WSEE at your fingertips
Free Android App
Free iPhone App
Free iPad App
Storm Tracker App
Droid
iPhone
iPad
All content © Copyright 2000 - 2014 WorldNow and WICU. All Rights Reserved.
For more information on this site, please read our Privacy Policy and Terms of Service.
                   WICU/WSEE - 3514 State Street Erie, PA 16508 - (814) 454-5201 - info@wicu12.com